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Kaletra

Kaletra
Customer rating:

4.4 out of 5(585 reviews)

5

(400)

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Product Info:

Category: HIV/AIDS Medication

Brand: Kaletra

Price: per bottle

Savings:

In Stock: Yes

Other names for this medication: Lopimune®

Quantity:

Subtotal: USD 234.15

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  • General Info

    Kaletra is a medication used to treat and control HIV-1 infection in people who weigh at least 35 kg. Kaletra isn't a cure for HIV or AIDS. Kaletra works by decreasing the count of virus in blood and allowing the immunity to fight opportunistic infections.

    Other names for this medication:

    Lopimune®

    Similar Products:

    Abamune-L®, Epzicom, Duovir®, Synthivan®, Virataz R, Tenvir-EM®, Truvada, Viraday®, Atripla, Trioday®, Avonza, Triomune®, Emtri, Duovir-N®, Ritomune®, Norvir, Atazor®, Efavir®, Stocrin®, Sustiva®, Lamivir®, Combivir®, Abamune L®, Abalam®, A Bec L®, Abamune®, A Bec®, Virol®, Ziagen, Zidovir®, Viread, Tenvir®, Nevimune®, Viramune, Daruvir®, Prezista, Isentress®, Zepdon®

    Active Ingredient:

    Lopinavir, Ritonavir

    Description

    Kaletra is composed of two active compounds: Ritonavir (RTV) – a first generation HIV protease inhibitor and Lopinavir (ABT-378) – second generation HIV protease inhibitor.

    Indications:

    - treatment of HIV type 1 infection in combination with other anti-retroviral agents.

    MOA (mechanism of action):

    Lopinavir and Ritonavir are both HIV protease inhibitors. Ritonavir is used as a booster of Lopinavir's action. It inhibits the metabolism of Lopinavir, thereby increasing the plasma levels of Lopinavir. Protease inhibitors bind to the protease active site and inhibit the activity of this enzyme. This averts cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Ritonavir and Lopinavir are active against HIV-2.

    Dosage

    For adults:

    The recommended dose is 400 mg/100 mg twice a day (every 12 hours), in combination with other anti-HIV agents.

    Adult patients who have not previously taken other antiviral drugs can also take Kaletra tablets once daily as an 800 mg/200 mg dose.

    Your doctor will advise on how many tablets should be taken.

    Adult patients who have previously taken other antiviral drugs can take Kaletra tablets once daily as an 800 mg/200 mg dose if their doctor decides it is appropriate.

    Kaletra must not be taken once daily with efavirenz, nevirapine, carbamazepine, phenobarbital, and phenytoin.

    Kaletra tablets can be taken with or without food.

    Do not stop or change the daily dose of Kaletra without first consulting with your doctor.

    For children of 2 years of age and older:

    For children, your doctor will determine the right dose (number of tablets) based on the child’s height and weight:

    - 15-25 kg: 2 tablets (100 mg / 25 mg) twice daily.

    - 25-35 kg: 3 tablets (100 mg / 25 mg) twice daily.

    - 35 kg and more: 3 tablets (100 mg / 25 mg) twice daily or 2 tablets (200 mg / 50 mg).

    Kaletra tablets can be taken with or without food.

    Lopinavir/Ritonavir oral solution is available for children with a BSA (body surface area) less than 0,6 m 2 or those who are unable to reliably swallow a tablet.

    Some people who take Kaletra may experience:

    - Liver problems. Some people taking Kaletra in combination with other anti-HIV medicines have developed liver problems. Contact your healthcare provider immediately if the signs of liver problems occur.

    - Changes in the electrical activity of the heart called PR prolongation. PR prolongation can cause irregular heartbeats.

    - Immune reactivation syndrome (severe immune deficiency during combination anti-retroviral therapy (CART) may lead to arousal of opportunistic infections and cause serious clinical conditions).

    - Increase in cholesterol and triglyceride levels.

    - Diabetes and high blood sugar (hyperglycemia). Tell your healthcare provider if you notice an increase in thirst or frequent urination.

    - Change in body fat (fat accumulates in the upper back and neck (“buffalo hump”), breast, and around the middle part of your body (trunk).

    - Increased bleeding for hemophiliacs.

    Precautions:

    HIV can be transmitted through sexual contact with HIV positive partner, blood (e.g., sharing needles, handling blood instruments, receiving blood transfusions, blood products, or organ/tissue transplants that were infected with HIV), childbirth, toiletries (razors and toothbrushes). Therefore, both HIV-positive and HIV-negative individuals are advised to have any kind of sex using a latex or polyurethane condom, avoid sharing needles or other things like toothbrushes or razors. It is important to discuss with doctor the precautions needed to avoid infecting other people as well as take precautions not to get infected.

    If you are currently using an oral contraceptive or using a patch contraceptive to prevent pregnancy, you should use an additional or different type of contraception (e.g. condom) as Kaletra may reduce the effectiveness of oral and patch contraceptives.

    Women who are HIV-positive must not breastfeed because HIV infection can be passed on to the baby in breast milk.

    Missing a dose

    If you take Kaletra once daily: if you notice within 12 hours of the time you usually take Kaletra, you must take the tablet(s) as soon as possible. Always take the tablet with food and with a dose of your other protease inhibitor. Then take the next dose as usual. If you notice 12 hours or more after the time you usually take Kaletra, then do not take the missed dose. Wait and take the next dose, with food, at your usual time. Do not take a double dose to make up for missing one.

    If you take Kaletra twice daily: if you notice within 6 hours of the time you usually take Kaletra, you must take the tablet as soon as possible. Always take the tablet with food and with a dose of your other protease inhibitor. Then take the next dose as usual. If you notice 6 hours or more after the time you usually take Kaletra, then do not take the missed dose. Wait and take the next dose, with food, at your usual time. Do not take a double dose to make up for missing one.

    Overdose

    If an overdose occurs and you are not feeling well, stop taking the medication immediately. You should seek emergency medical attention or contact your healthcare provider immediately.

    Storage

    Store Kaletra tablets or oral powder at room temperature between 68-77 degrees F (20-25 degrees C). Keep Kaletra in the original container. Do not use Kaletra if the seal over the bottle opening is broken or missing. Keep the bottle tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

  • Safety Information

    Kaletra is a medication used to treat and control HIV-1 infection in people who weigh at least 35 kg. Kaletra isn't a cure for HIV or AIDS. Kaletra works by decreasing the count of virus in blood and allowing the immunity to fight opportunistic infections.

    Other names for this medication:

    Lopimune®

    Similar Products:

    Abamune-L®, Epzicom, Duovir®, Synthivan®, Virataz R, Tenvir-EM®, Truvada, Viraday®, Atripla, Trioday®, Avonza, Triomune®, Emtri, Duovir-N®, Ritomune®, Norvir, Atazor®, Efavir®, Stocrin®, Sustiva®, Lamivir®, Combivir®, Abamune L®, Abalam®, A Bec L®, Abamune®, A Bec®, Virol®, Ziagen, Zidovir®, Viread, Tenvir®, Nevimune®, Viramune, Daruvir®, Prezista, Isentress®, Zepdon®

    Active Ingredient:

    Lopinavir, Ritonavir

    Side effects

    The most common and uncommon side effects associated with Kaletra are:

    • diarrhea
    • nausea
    • upper respiratory tract infection
    • inflammation of the pancreas
    • vomiting
    • enlarged abdomen
    • pain in the lower and upper stomach area
    • passing wind
    • indigestion
    • decreased appetite
    • reflux from your stomach to the esophagus which may cause pain
    • swelling or inflammation of the stomach, intestines, and colon
    • increased cholesterol levels in your blood, increased triglycerides levels in your blood, high blood pressure
    • low number of red and white blood cells
    • rash, eczema, accumulation of scales of greasy skin
    • dizziness, anxiety, difficulty in sleeping
    • feeling tired
    • headache
    • hemorrhoids
    • inflammation of the liver including increased liver enzymes
    • allergic reactions including hives and inflammation in the mouth
    • lower respiratory tract infection
    • enlargement of the lymph nodes
    • impotence
    • abnormally heavy or extended menstrual flow or a lack of menstruation
    • muscle weakness and spasms
    • pain in the joints
    • pain in muscles and back
    • damage to nerves of the peripheral nervous system
    • night sweats
    • infection of the skin
    • inflammation of skin or hair pores
    • accumulation of fluid in the cells or tissues

    Side effects occurrence does not only depend on the medication you are taking, but also on your overall health and other factors.

    Contraindications

    Kaletra is contraindicated in patients who are allergic to Lopinavir, Ritonavir or any of the other ingredients of Kaletra.

    Do not take Kaletra if you have kidney, liver problems, hepatitis B or C and, hemophilia, diabetes mellitus, erectile dysfunction.

    Do not combine Kaletra with such medications as astemizole or terfenadine (for allergy symptoms); oral midazolam or triazolam (for anxiety and/or trouble sleeping); pimozide (for schizophrenia); quetiapine (used to treat schizophrenia, bipolar disorder and major depressive disorder); lurasidone (for depression); ranolazine (for chronic chest pain [angina]); cisapride (for relieve certain stomach problems); ergotamine, dihydroergotamine, ergonovine, methylergonovine (for headaches); amiodarone, dronedarone (used to treat abnormal heart beat); lovastatin, simvastatin (used to lower blood cholesterol); alfuzosin (used in men to treat symptoms of an enlarged prostate (benign prostatic hyperplasia (BPH)); fusidic acid (for skin infections caused by Staphylococcus bacteria such as impetigo and infected dermatitis); elbasvir/grazoprevir (for chronic hepatitis C virus (HCV)); ombitasvir/paritaprevir/ritonavir with or without dasabuvir (used to treat chronic hepatitis C virus [HCV]); avanafil or vardenafil (for erectile dysfunction); sildenafil used to treat pulmonary arterial hypertension (PAH); products that contain St John’s wort.

    Do not have any kind of sex without using a latex or polyurethane condom.

    Do not share needles or other things like toothbrushes or razors.

    Do not take Kaletra if you are pregnant or plan to have a baby. First, consult your healthcare provider.

    Women who are HIV-positive must not breastfeed because HIV infection can be passed on to the baby in breast milk.

  • F.A.Q.

    Kaletra is a medication used to treat and control HIV-1 infection in people who weigh at least 35 kg. Kaletra isn't a cure for HIV or AIDS. Kaletra works by decreasing the count of virus in blood and allowing the immunity to fight opportunistic infections.

    Other names for this medication:

    Lopimune®

    Similar Products:

    Abamune-L®, Epzicom, Duovir®, Synthivan®, Virataz R, Tenvir-EM®, Truvada, Viraday®, Atripla, Trioday®, Avonza, Triomune®, Emtri, Duovir-N®, Ritomune®, Norvir, Atazor®, Efavir®, Stocrin®, Sustiva®, Lamivir®, Combivir®, Abamune L®, Abalam®, A Bec L®, Abamune®, A Bec®, Virol®, Ziagen, Zidovir®, Viread, Tenvir®, Nevimune®, Viramune, Daruvir®, Prezista, Isentress®, Zepdon®

    Active Ingredient:

    Lopinavir, Ritonavir

    Q: What is Kaletra used for?

    A: Kaletra is a medication used to treat and control HIV-1 infection in people who weigh at least 35 kg. Kaletra isn't a cure for HIV or AIDS. Kaletra works by decreasing the count of virus in blood and allowing the immunity to fight opportunistic infections.

    Q: Can I have sex when taking Kaletra?

    A: You should know neither Kaletra nor any other anti-retroviral medication can cure HIV. It is therefore important that you have safe sex and take other precautions to avoid passing HIV on to other people. Do not have any kind of sex without using a latex or polyurethane condom.

    Q: Can I breastfeed if I take Kaletra?

    A: Women who are HIV-positive must not breastfeed because HIV infection can be passed on to the baby in breast milk.

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    EMS  USD 25.00

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